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目的报告三氧化二锑(Antimony trioxide,Sb2O3)致职业性接触性皮炎的临床表现和治疗经过。方法对广西某厂198名从事Sb2O3作业工人进行职业健康检查,将皮肤科的检查结果进行归纳分析。结果发现Sb2O3粉尘致皮损主要以局部皮肤粟粒样大小丘疹为主,丘疹多为圆形或类圆形,患者往往伴有不同程度的剧痒,诊断为职业性接触性皮炎。一般病例给予抗阻胺类药口服3～5 d,严重病例在给予抗生素严格控制感染的同时,给予地塞米松静脉滴注1～2周均可痊愈。结论在198名Sb2O3作业工人中有53名诊断为职业性接触性皮炎,发病率达到26.77%,是广西常见的职业危害之一。
Objective To report the clinical manifestation and treatment of occupational contact dermatitis caused by antimony trioxide (Sb2O3). Methods An occupational health examination was conducted on 198 workers engaged in Sb2O3 in a factory in Guangxi. The results of dermatology examination were summarized. The results showed that the skin lesions caused by dust Sb2O3 mainly in local skin miliary-sized papules, papules mostly round or round, patients often accompanied by varying degrees of itching, the diagnosis of occupational contact dermatitis. General cases of oral administration of anti-amine drugs 3 ~ 5 d, severe cases given antibiotics strictly controlled infection at the same time, giving dexamethasone intravenous infusion of 1 to 2 weeks can be cured. Conclusion Among the 198 Sb2O3 workers, 53 were diagnosed as occupational contact dermatitis with a morbidity of 26.77%, which is one of the common occupational hazards in Guangxi.