Rno_circ_0005139 regulates apoptosis by targeting Wnt5a in rat anorectal malformations

• 作 者: Dan Liu Yuan Qu Zheng-Nong Cao
• 机 构: DepartmentofPediatricSurgery
• 出 处: 世界胃肠病学杂志:英文版
• 发表日期: 2020年29期
• 关键词: Anorectal malformation Circular RNA MICRORNA WNT5A Rno_circ_0005139
• 基金项目: Supported by the National Natural Science Foundation of China,No.81671503.,Institutional animal care and use committee statement:All animal experiments conformed to the internationally accepted princi

BACKGROUND The molecular mechanisms underlying anorectal malformations(ARM)are not fully established.Circular RNAs(circRNAs)are new born non-coding RNAs,and their role in ARM is unclear.We assumed that rno_circ_0005139 influences apoptosis and proliferati