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目的:观察动态血糖监测仪(continuous glucose monitoring system,CGMS)联合胰岛素泵(insulin pump)治疗妊娠糖尿病的临床效果。方法:42例妊娠糖尿病患者均采用胰岛素泵持续皮下输注(continuous subcutaneous insulin infusion,CSⅡ)进行治疗,其中22例(微量血糖仪组)采用每天8次微量血糖仪监测,20例(CGMS组)在每天8次微量血糖仪监测基础上采用CGMS监测血糖,对2者血糖稳定达标天数和低血糖发生次数进行比较。结果:CGMS组血糖稳定达标所需天数3.21±0.85天,少于微量血糖仪组5.04±1.27天(P<0.01)。而CGMS组低血糖发现次数显著高于微量血糖仪组(P<0.01)。结论:胰岛素泵联合CGMS与胰岛素泵联合微量血糖仪监测治疗妊娠糖尿病均能很好控制血糖,胰岛素泵联合CGMS临床达标时间短,易发现低血糖事件。
Objective: To observe the clinical effect of continuous glucose monitoring system (CGMS) combined with insulin pump on gestational diabetes mellitus. Methods: Forty - two patients with gestational diabetes mellitus were treated with continuous subcutaneous insulin infusion (CS Ⅱ). Twenty - two patients (DMEM group) were monitored with 8 times glucose meter daily and 20 cases (CGMS group) Blood sugar was monitored by CGMS on the basis of 8 times a day glucose monitoring, and the number of days of stable glycemic control and the number of hypoglycemia were compared. Results: The number of days required for glycemic control in CGMS group was 3.21 ± 0.85 days, less than that in the micro-glucose meter group 5.04 ± 1.27 days (P <0.01). However, the number of hypoglycemia found in CGMS group was significantly higher than that in micro-glucose meter group (P <0.01). Conclusion: Insulin pump combined with CGMS and insulin pump combined with micro-glucose meter for the treatment of gestational diabetes mellitus can control blood sugar well. Insulin pump combined CGMS clinical short-time, easy to find hypoglycemic events.