【摘 要】
：
目的:掌握广西壮族自治区南溪山医院药品不良反应(ADR)的发生特点,为临床合理用药提供参考.方法:对2006年1月-2010年12月收集的321例ADR报告,按患者性别、年龄、给药途径、AD
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目的:掌握广西壮族自治区南溪山医院药品不良反应(ADR)的发生特点,为临床合理用药提供参考.方法:对2006年1月-2010年12月收集的321例ADR报告,按患者性别、年龄、给药途径、ADR程度、药品类别、涉及器官和(或)系统以及临床表现等进行统计、分析.结果:321例ADR中,19 ～44岁年龄段患者ADR发生率较高(113例,占35.2％),男性与女性间无差异；静脉给药方式是导致ADR的重要途径(248例,占77.3％);ADR发生率最高的为抗感染药(139例,占43.3％),其次是消化系统用药及中药制剂；临床表现以皮肤及其附件损害最常见(163例,占50.8％),其次是全身性损害.结论:应加强抗菌药物及中药制剂的合理使用与管理,以减少ADR发生；同时加强ADR监测的培训工作,提高上报意识,完善并提高ADR报告质量.
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