【摘 要】
：
Objective:To study the efficacy of Chinese medicine (CM) on isolated systolic hypertension.Methods:Seven electronic databases were searched for randomized controlled trials (RCTs) published until August 2015.Subgroup analyses and meta-analysis were perfor
【机 构】
：
Department of Cardiovascular Diseases, Guang’anmen Hospital,China Academy of Chinese Medical Science
论文部分内容阅读
Objective:To study the efficacy of Chinese medicine (CM) on isolated systolic hypertension.Methods:Seven electronic databases were searched for randomized controlled trials (RCTs) published until August 2015.Subgroup analyses and meta-analysis were performed to assess the efficacy and safety of the included studies.Results:A total of 24 studies,including 2,096 patients (1,058 patients in the intervention group and 1,038 in the control group),were evaluated in the final analysis.Compared with a conventional therapy used alone,CM as additional intervention was more effective on systolic blood pressure [mean difference (MD)=-0.66,95％ confidence interval (CI)=(-0.97,-0.36),P＜0.00001] and significantly diminished the pulse pressure [MD=-7.49,CI=(-12.69,-2.29),P＜0.00001].However it showed no additional benefit on diastolic blood pressure [MD=1.16,CI=(0.02,2.29),P=0.87].Adverse events were not explicitly reported in most RCTs.Conclusions:CM might be a promising approach for the elderly with isolated systolic hypertension,while the evidence for CM employed alone was insufficient.Considering the inherent limitations of the included studies,larger high-quality RCTs with extensive follow-up should be performed to validate our findings in the future.
其他文献
Objective:To observe the alteration of QT dispersion (QTd) and QTc dispersion (QTcd) in hemodialysis patients after oral administration of Zhigancao Decoction (炙甘草汤,Roasted Licorice Decoction,RLD).Methods:To investigate the alteration of QTd and QTcd in 6
It has been well known that insomnia and sleep deprivation can lead to many metabolic diseases such as type 2 diabete mellitus (T2DM).Chinese medicine (CM) has been used to improve insomnia and showed many good therapeutic effects.Some Coptidis Rhizoma-co
Objective:To evaluate the quality and consistency of recommendations in the clinical practice guidelines (CPGs) for hypertension in Chinese medicine (CM).Methods:CM CPGs were identified from 5 electronic databases and hand searches through related handboo
The number of people with chronic diseases rises rapidly in recent years worldwide.Except for drug medication,mind-body exercises are indispensable for chronic disease management.Traditional Chinese practice (TCP),as an integrative intervention,is known a
Objective:To investigate the anti-leukemia effect of total saponins of Rubus parvifolius L.(TSRP) on K562 cell xenografts in nude mice and the mechanisms of action.Methods:The K562 cell xenografts in nude mice were established,and then randomly divided in
Objective:To evaluate the effects of Aidi Injection (艾迪注射液,AD) in combination with Western medical therapies (WMT) in patients with primary liver cancer (PLC).Methods:Randomized controlled trials (RCTs) comparing AD plus WMT with WMT alone were retrieved
Objective:To study the expression level and role of apoptosis-associated speck-like protein containing a caspase recruitment domain (PYCARD) gene transcript variant mRNA in peripheral blood mononuclear cells (PBMCs) of primary gout (PG) patients with diff
Objective: To explore the effectiveness and safety of acupuncture in patients with post-stroke dysphagia by an update meta-analysis. Methods: Potentially eligible RCTs aimed to evaluate the effects of acupuncture vs. non-acupuncture treatments, such as re
Objective:To understand patient satisfaction with acupuncture appointment duration for the first and subsequent appointments in the plan of care,time spent with the acupuncture provider,willingness to pay for longer duration appointments,and lack of insur
Objective:To observe the effects of Huannao Yicong Formula(还脑益聪方, HYF) on learning and memory and it\'s regulating effect on γ,-secretase related anterior pharynx defective 1 (APH-1),presenilin enhancer-2 (PEN-2) signaling pathway,so as to discuss and f