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一、前言被动免疫疗法治疗恶性肿瘤是人们长期以来不断探索的一个课题,其中包括使用抗体或免疫潘性细胞进行治疗,后者又称过继性免疫治疗。抗体易于制备和保存,从五十年代起就已开始着手这一方面的工作,但在动物实验中很少有取得明确疗效者。在人类也进行了一些尝试:有的使用经瘤细胞免疫后的志愿者的血清,或痊愈后肿瘤患者的血清,有的使用肿瘤细胞免疫后的动物的血清,但均未获得满意结果。近年来,随着单克隆抗体技术的进展,
I. Introduction Passive immunotherapy for the treatment of malignant tumors has long been a subject of continuous exploration, including the use of antibodies or immune pancytopenia for treatment, which is also known as adoptive immunotherapy. Antibodies are easy to prepare and preserve, and work has been underway since the 1950s, but few have been shown to be effective in animal experiments. Some attempts have also been made in human beings. Some people use serum from volunteers after tumor cell immunization, or serum from cured tumor patients, and some animals from mice immunized with tumor cells. However, satisfactory results have not been obtained. In recent years, with the progress of monoclonal antibody technology,