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急性灭鼠剂敌溴灵(Dixiulin)是溴甲灵(Bromethalin)的化学衍生物。它对靶动物和非靶动物均毒。急性口服LD_(50)和95%可信限是:大白鼠0.86(0.77～0.96)、小白鼠1.62(1.51～1.74)、白化黑线仓鼠1.93(1.19～3.12)、草原黄鼠0.31(0.24～0.40)、臭鼩1.16(0.81～1.67)、鸡6.68(5.18～8.63)和猫0.838～4.542mg/kg。动物中毒潜伏期长,症状反应轻。靶动物对该药接受性好。大、小白鼠摄食0.005～0.01%敌溴灵毒饵杀灭率为90～100%。接受亚致死量的大、小白鼠有轻微的蓄积中毒反应。蓄积中毒系数K值分別为5.06和19.2。在养鸡场、养猪场和农村居民住宅使用0.005%、0.015%和0.010%敌溴灵毒饵杀灭褐家鼠和小家鼠,灭鼠效果分别为91.24%、88.87%和82.98%。在草原使用0.005%、0.01%和0.02%敌溴灵小麦毒杀草原黄鼠,灭鼠率分别为52.30%、83.20%和90.00%。此药可做为现用急性灭鼠剂的替换药。
Acute Rodenticide Dixiulin is a chemical derivative of Bromethalin. It is toxic to both target and non-target animals. The acute oral LD 50 and 95% confidence limits were 0.86 (0.77 ~ 0.96) in rats, 1.62 (1.51 ~ 1.74) in mice, 1.93 (1.19 ~ 3.12) in albino black hamsters, 0.31 0.40), stinkbugs 1.16 (0.81-1.67), chicken 6.68 (5.18-8.63) and cats 0.838-4.452 mg / kg. Animal poisoning long latency, mild symptoms. The target animal has good acceptance of the drug. Large, white mouse feeding 0.005 ~ 0.01% Eupatorium poison bait kill rate of 90 to 100%. Sub-lethal dose of large, white mice have a slight accumulation of toxic reactions. Accumulation poisoning coefficient K values were 5.06 and 19.2. In rodent farms, pig farms and rural residences, the brown house mice and the white house mice were killed with the bait of 0.005%, 0.015% and 0.010% respectively. The anti-rodent effects were 91.24%, 88.87% and 82.98% respectively. The use of 0.005%, 0.01% and 0.02% Eupromurum poisoning grass carp to kill steppe in the grassland were 52.30%, 83.20% and 90.00% respectively. This medicine can be used as a replacement for the current acute rodenticide.