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目的 探讨川芎嗪预防脑卒中复发的作用。方法 持续 5年用川芎嗪治疗脑卒中后恢复期患者 171例 (治疗组 ) ,观察治疗后患者神经功能缺损积分、脑卒中的复发率及血液流变学的改变 ,并与同期的脑卒中恢复期患者 16 4例 (对照组 )进行比较。结果 治疗组脑卒中复发率、全血粘度、血浆比粘度及纤维蛋白原均明显低于对照组 ,而总有效率明显高于对照组。结论 川芎嗪可能通过改善脑卒中恢复期患者的脑血液循环而降低脑卒中的复发率
Objective To investigate the effect of ligustrazine in preventing the recurrence of stroke. Methods 171 patients (treatment group) were treated with ligustrazine for 5 consecutive years after recovery from stroke, and the neurological deficit scores, recurrence rate and hemorheology of the patients were observed and compared with the same stroke recovery 16 4 patients (control group) were compared. Results The recurrence rate, whole blood viscosity, plasma viscosity and fibrinogen of the treatment group were significantly lower than those of the control group, but the total effective rate was significantly higher than that of the control group. Conclusion Tetramethylpyrazine may reduce the recurrence rate of stroke by improving cerebral blood circulation in patients with convalescent stroke