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为探讨低水平铅暴露人群体内游离红细胞原卟啉（ Ｆ Ｅ Ｐ）与血铅（ Ｐｂ Ｂ）的关系，在严格的质量保证措施下，对北京石景山地区２７０ 名孕妇及其婴幼儿进行了游离红细胞原卟啉及血铅的追踪研究。结果显示：孕妇血中 Ｆ Ｅ Ｐ水平为３１７～３８３ μｇ／ｄ Ｌ（ｎ＝ ５７８），脐带血中 Ｆ Ｅ Ｐ水平为４８８±２３６ μｇ／ｄ Ｌ（ｎ＝ １３３），婴幼儿各年龄组间 Ｆ Ｅ Ｐ水平无显著性差异，为３７２～３９５ μｇ／ｄ Ｌ（ｎ＝ ３５７），与正常人群的水平接近。本研究中无论孕妇还是婴幼儿，血铅值大部分低于０４８３μｍ ｏｌ／ Ｌ（１００ μｇ／ Ｌ）。经相关性分析，ｌｎ Ｆ Ｅ Ｐ与血铅值之间无相关关系（ Ｐ＞ ００５）。因此在低血铅水平， Ｆ Ｅ Ｐ测定不能作为铅暴露的监测指标。
To investigate the relationship between free erythrocyte protoporphyrin (F E P) and blood lead (Pb B) in low-level lead exposure population, 270 pregnant women and their infants in Shijingshan district of Beijing were freed under strict quality assurance measures Tracking of erythrocyte protoporphyrin and blood lead. The results showed that the level of F E P in pregnant women was 317 ~ 383 μg / d L (n = 578), and the level of F E P in umbilical cord blood was 488 ± 236 μg / d L (n = 133). There was no significant difference in FEP among infants and young children in all age groups, ranging from 372 to 395 μg / d L (n = 357), which was similar to that in normal subjects. In this study, most of the blood lead values were lower than 0 483 μmol / L (100 μg / L) in pregnant women and infants. Correlation analysis showed no correlation between lnFEP and blood lead (P> 005). Therefore, at low blood lead level, the FEP measurement can not be used as a monitoring indicator of lead exposure.