A Ttach lmportance to Vascular lmplications of Kruppel-like Factors

• 作 者: 范自力 贺石林
• 出 处: 血栓与止血学
• 发表日期: 2009年5期
• 关键词: Kru ppel-like factors Vascular endothelial cell Atherosclerosis Thrombosis

Kruppel-like factors(KLFs) are a subclass of the zinc finger family of DNA-binding transcription factors. The nomenclature is based on the homology to the DNA-binding domain of the drosophila protein kruppel. To date,17 members of KLF family have been identified in mammalian cells.