Construction and characterization of infectious cDNA clones of enterovirus 71(EV71)

来源 :Virologica Sinica | 被引量 : 0次 | 上传用户:ytw2001
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Dear Editor,Enterovirus 71(EV71),a member of the genus Enterovirus of the family Picornaviridae,is a single-stranded,positive-sense RNA virus that usually causes mild handfoot-mouth disease(HFMD)in children,with symptoms such as fever,diarrhea,and herpangina(Liu et al.,2013).However,certain strains of EV71 infection can cause severe neurological complications,such as SDLY107(Sun et al.,2014).EV71 is classified into three distinct genotypes(A–C);the B and C genotypes are further divided into B1–B5 and C1–C5 genotypes,respectively,based on Dear Editor, Enterovirus 71 (EV71), a member of the genus Enterovirus of the family Picornaviridae, is a single-stranded, positive-sense RNA virus that usually causes mild hand-foot disease (HFMD) in children, with symptoms such as fever (Liu et al., 2013). Certainly, EV71 infection can cause severe neurological complications such as SDLY107 (Sun et al., 2014). EV71 is classified into three distinct genotypes ); the B and C genotypes are further divided into B1-B5 and C1-C5 genotypes, respectively, based on
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