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分化较好的甲状腺癌能产生进入血液的甲状腺球蛋白,这种被恶性肿瘤产生的情况很不常见,我们随访了一例患滤泡状甲状腺癌且有甲状腺机能亢进症临床和生化证据的患者,并对该病人发病机制进行了解释。病例报告:患者女性70岁,近来发现颈部饱满,体重下降,颈部未触及淋巴结,放射性同位索显象示两肺及部分骨骼有侵润现象,~(90m)Tc甲状腺显象显示腺体中度肿大,~(99m)Tc吸收不良,右叶有多个~(99m)Tc吸收减低区,骨活检证实为滤泡状甲状腺癌。患者临床表现甲状腺机能亢进症状,生化检查与其相符合(表1),血清TSIg(甲状腺刺激免疫球蛋白)明显增高;大约相当于TSH 32μU/ml。
Well-differentiated thyroid cancer can produce thyroglobulin into the bloodstream. This is a rare case of malignancy. We followed a patient with follicular thyroid cancer who had clinical and biochemical evidence of hyperthyroidism, The pathogenesis of this patient was explained. Case Report: Female patients 70 years of age, recently found a full neck, weight loss, the neck did not reach the lymph nodes, radioisotope imaging showed two lungs and some bones have infiltration, ~ (90m) Tc thyroid imaging showed gland Moderate swelling, ~ (99m) Tc malabsorption, the right lobe has a number of ~ (99m) Tc absorption reduction zone, bone biopsy confirmed as follicular thyroid cancer. Patients with clinical symptoms of hyperthyroidism, biochemical tests consistent with it (Table 1), serum TSIg (thyroid-stimulated immunoglobulin) was significantly increased; approximately equivalent to TSH 32μU / ml.