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目的探讨坦索罗辛联合通癃启闭汤治疗前列腺增生(BPH)患者的临床疗效。方法选取2014年2月至2015年2月阜新市中医院收治的BPH患者148例为研究对象,按随机数字表法分为对照组和观察组,各74例。对照组患者口服坦索罗辛,观察组患者在对照组基础上服用通癃启闭汤,比较两组患者治疗前后的国际前列腺症状(IPSS)评分、症状性BPH剩余尿(PVR)、最大尿流率(Qmax)以及临床疗效。结果观察组患者的总有效率为94.6%,明显高于对照组的82.4%,差异有统计学意义(P<0.05);观察组患者的IPSS评分明显低于对照组,PRV明显少于对照组,Qmax明显大于对照组,差异均有统计学意义(均P<0.05)。结论坦索罗辛联合通癃启闭汤治疗BPH患者,能明显改善其临床症状,疗效甚佳。
Objective To investigate the clinical effect of tamsulosin combined with Tongluo Kaiji Tang in the treatment of benign prostatic hyperplasia (BPH). Methods A total of 148 patients with BPH admitted to Fuxin Hospital of Traditional Chinese Medicine from February 2014 to February 2015 were selected as study subjects and divided into control group and observation group according to random number table method, with 74 cases in each group. The patients in the control group were given tamsulosin orally and the patients in the observation group were given Tonglu Kai Tang on the basis of the control group. The scores of International Prostate Symptoms (IPSS), Symptomatic BPH Residual Urinary (PVR) Flow rate (Qmax) and clinical efficacy. Results The total effective rate of the observation group was 94.6%, which was significantly higher than that of the control group (82.4%) (P <0.05). The IPSS score of the observation group was significantly lower than that of the control group, and the PRV was significantly less than that of the control group , Qmax was significantly greater than the control group, the difference was statistically significant (P <0.05). Conclusion Tamsulosin combined Tongluo Kaihuitang treatment of BPH patients, can significantly improve their clinical symptoms, the effect is very good.