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在125例外周血淋巴细胞G显带染色体检查中发现10例散发性t(7;14)易位。其中7例均发现于滋养细胞瘤患者夫妇中,频率高达7/47(患者3/30,患者丈夫4/17);2例为年轻的初孕妇。在22例卵巢瘤和14例其他妇科肿瘤患者中仅1例,而在22例妻子生育史正常的男性中未发现1例。
Ten cases of sporadic t (7; 14) translocations were found in G banding of 125 peripheral blood lymphocytes. Of these, 7 were found in couples with gestational trophoblastic disease at a frequency of up to 7/47 (3/30 of the patients and 4/17 of the husbands) and 2 as young early pregnant women. Only 1 out of 22 ovarian tumors and 14 other gynecologic cancers were found, whereas in 22 men whose normal fertility history was not found in 1 case.