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目的:探究尼莫地平治疗蛛网膜下腔出血的机制及其临床疗效。方法:选取我院收治的102例蛛网膜下腔出血患者,随机分为对照组和治疗组,对照组常规止血治疗,治疗组在此基础上注射尼莫地平治疗。利用颅内压监护仪对两组患者进行1、4、7、10d的连续监测并记录;治疗4周后通过CT复查头颅,判定前后患者恢复及并发症情况;3个月随访进行GOS分值记录。结果:通过连续的颅压监测,治疗组在第7天与第10天时颅压值明显低于对照组(P<0.05);治疗组的有效率为92.16%,明显高于对照组;治疗组再出血、脑血管痉挛、脑积水发生率较对照组低。结论:蛛网膜下腔出血的早期治疗中加入尼莫地平静脉注射,能获得良好的治疗效果。
Objective: To investigate the mechanism and clinical efficacy of nimodipine in the treatment of subarachnoid hemorrhage. Methods: A total of 102 patients with subarachnoid hemorrhage admitted to our hospital were randomly divided into control group and treatment group. The control group received conventional hemostasis. The treatment group was treated with nimodipine. The intracranial pressure monitor was used to monitor and record the two groups of patients for 1, 4, 7, and 10 days continuously. After 4 weeks of treatment, the skull was examined by CT to determine the recovery and complications before and after treatment. The GOS scores recording. Results: The intracranial pressure in the treatment group was significantly lower than that in the control group on day 7 and 10 (P <0.05) by continuous intracranial pressure monitoring. The effective rate of the treatment group was 92.16%, which was significantly higher than that of the control group. The treatment group Rebleeding, cerebral vasospasm, hydrocephalus incidence was lower than the control group. Conclusion: The early treatment of subarachnoid hemorrhage by adding nimodipine intravenous injection, can get a good therapeutic effect.