在 6-desaturase 和 MEK/ERK1/2 小径的 stearoyl-CoA desaturase 1: 角色的 PPAR 导致收缩筋的改变

• 作 者: Negar Saliani Masoud Darabi Ba
• 机 构: DrugAppliedResearchCenter,DepartmentofBiochemistryandClinicalLaboratories,ImmunologyResearchCenter,D
• 出 处: 世界肝病学杂志：英文版（电子版）
• 发表日期: 2013年4期
• 关键词: PIOGLITAZONE PD98059 6-desaturase Stearoyl-CoA DESATURASE HepG2 cells Pioglitazo
• 基金项目: Supported by A Grant from the Drug Applied Research Center of Tabriz University of Medical Sciences,to Darabi M,Research Projects numbers 89/102 and 90/73

AIM:To investigate the effect of MEK/ERK1/2 pathway on peroxisome proliferator-activated receptors(PPARγ)agonist-induced alterations in Δ6-desaturase(Δ6D)and stearoyl-CoA desaturase 1(SCD1)in hepatocellular carcinoma cell line HepG2.METHODS:HepG2 cells cu