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通过对１０８５８例肝脏毒物作业者１０～１７年来定期体检资料加以整理、分析，检出可疑慢性中毒性肝病患者１５１４例，这些病例经多年观察，未能确诊的原因是：①目前所用肝功能试验不够敏感；②诊断习惯上用排除法，临床思维有局限性；③缺乏诊断标准。针对以上问题，采用：①分析动态观察资料，从中明确肝脏损害的时间及程度；②探索较敏感的指标；③综合劳动卫生及临床资料，取得初步诊断意见，再做好鉴别诊断，得出明确结论。用以上方法使１５１４例对象中，１０３５例得到确诊。本研究提出诊断本病的临床思维及方法。
By analyzing 10858 cases of hepatic toxicants from 10 to 17 years of regular physical examination, 1514 cases of suspicious chronic toxic liver disease were analyzed. The reasons for these cases after several years of observation were as follows: (1) The liver function tests Not sensitive enough; ② diagnostic methods used to rule out the use of clinical thinking limitations; ③ lack of diagnostic criteria. For the above problems, the use of: ① analysis of dynamic observation data, from which a clear time and extent of liver damage; ② explore more sensitive indicators; ③ integrated labor and health and clinical data to obtain preliminary diagnosis, and then differential diagnosis, to make clear in conclusion. Of the 1514 subjects, 1035 were confirmed by the above method. The study proposed the diagnosis of the disease clinical thinking and methods.