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目的 分析服用及停用雷公藤糖浆后患者精子密度的变化及生育恢复情况。方法 采用ＷＨＯ 的标准，对３３ 例服用雷公藤糖浆的强直性脊柱炎患者的精液进行分析，并调查和随访其生育情况。结果 服药期间，３３例患者精液检查均有精子密度为零或接近零的记录；停药１２０ ｄ（４ 个月） 以上，精子密度均见显著提高；３３ 例雷公藤糖浆服用者中，１３ 例的妻子有孕育史。结论 雷公藤糖浆可致男性精子密度降低至零，停药后可以恢复生育
Objective To analyze the change of spermatozoon density and recovery of children after taking Tripterygium wilfordii syrup. Methods The WHO criteria were used to analyze the semen of 33 patients with ankylosing spondylitis treated with Tripterygium wilfordii syrup and to investigate and follow up their fertility. Results During the medication period, sperm density was zero or close to zero in all the semen samples of 33 patients. Significantly higher sperm density was observed in 120 d (4 months) after drug withdrawal. Among the 33 patients with tripterygium wilfordii syrup, 13 His wife has a history of gestation. Conclusion Tripterygium wilfordii syrup can cause male sperm density reduced to zero, after stopping the treatment can restore fertility