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随着甲氰脒胍的广泛应用,由此引起的急性肾损害,国外陆续有个案报导。我院收治1例由甲氰脒胍引起氮质血症及精神紊乱,现报导如下。患者,女,103岁,因摔伤后左髂疼痛及活动障碍5小时,于1984年2月6日急诊入院。查体:体温37.8℃,脉搏84次/min,血压110/80mmHg。神志清楚,左额软组织撕裂,两肺散在干湿罗音,心脏无异常发现。X 线摄片示肺部感染,左股骨粗隆间骨折。化验室检查:Hb 6.1g,WBC8000,中性88%;尿常规(-),尿素氮2.2mg%。即予青霉素治疗,并于7日晚加庆大霉素8万单位肌注一次。
With the wide application of cimetidine, resulting in acute renal damage, one after another case report. 1 case admitted to our hospital caused by azamidine guanidine azotemia and mental disorders are reported as follows. The patient, female, 103 years old, was admitted to the emergency department on February 6, 1984 for 5 hours after falling injury due to left iliac pain and mobility disorder. Physical examination: body temperature 37.8 ℃, pulse 84 times / min, blood pressure 110 / 80mmHg. Consciousness, left frontal soft tissue tear, dry lungs scattered in both lungs, no abnormal heart found. X-ray showed pulmonary infection, left intertrochanteric fracture. Laboratory tests: Hb 6.1g, WBC8000, neutral 88%; urine routine (-), urea nitrogen 2.2mg%. Namely to penicillin treatment, and in the evening of the 7th plus gentamicin 80,000 units intramuscularly once.