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目的探讨慢乙肝肝衰竭患者血清免疫球蛋白变化及其临床意义。方法本次临床研究选取本院2013年1月~2014年3月之间收治的60例慢乙肝肝衰竭患者为观察对象,其中,30例慢性重型乙型肝炎(SHB),30例慢性乙型肝炎(CHB),同时选择30名健康体检者为对照组,对比分析三组患者血清免疫球蛋白水平。结果患者病情变化与其免疫球蛋白水平之间存在直接联系(P<0.05),且三组观察对象血清免疫球蛋白水平对比具有明显的统计学差异(P<0.05)。结论血清免疫球蛋白是慢乙肝肝衰竭患者最为常用的一种诊断和检查指标,能够为患者的临床治疗提供可靠依据。
Objective To investigate the changes of serum immunoglobulin in patients with chronic hepatitis B and its clinical significance. Methods Sixty patients with chronic hepatitis B liver failure treated in our hospital from January 2013 to March 2014 were selected as the observation subjects. Thirty patients with chronic severe hepatitis B (SHB), 30 patients with chronic hepatitis B Hepatitis (CHB). At the same time, 30 healthy subjects were selected as the control group, and the serum immunoglobulin levels were compared among the three groups. Results There was a direct correlation between the changes of the patient’s condition and the immunoglobulin levels (P <0.05). The serum immunoglobulin levels in the three groups were significantly different (P <0.05). Conclusions Serum immunoglobulin is the most commonly used diagnostic and testing index for patients with chronic hepatitis B liver failure, which can provide a reliable basis for the clinical treatment of patients.