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目的:探讨安神类中药饮片(简称SNCM)出现的不良反应(简称ADR),并思考用药警戒。方法:收集2013年5月到2015年5月之间医疗机构服用SNCM出现ADR的80例案例作为实际研究对象,分析其中80例ADR临床表现以及转归状况。结果:出现ADR状况的SNCM主要建立在朱砂基础上,而ADR主要是以损害脏器官为主,而出现该种ADR状况与患者过量用药以及自行用药和机体因素等有着紧密关联性。结论:加强对SNCM的药材贮存以及用法用量和相应使用禁忌方面的控制能够减少ADR状况出现。因此提高用药警戒对于SNCM有效合理应用至关重要。
Objective: To investigate the adverse reactions (referred to as ADR) appearing in the soothing category Chinese Herbal Medicine Pieces (referred to as SNCM), and to consider the medication alert. Methods: From May 2013 to May 2015, 80 cases of ADR patients taking SNCM in our medical institutions were collected as the actual subjects, and the clinical manifestations and outcome of 80 ADR cases were analyzed. Results: The SNC prevailing in ADR was mainly based on cinnabar, whereas ADR was predominantly damaging to organs. This ADR was closely related to patients’ overdose, self-medication and organism factors. CONCLUSIONS: Enhancing control over SNCM’s medicinal storage and its use and contraindications can reduce ADR conditions. Therefore, to improve the medication alert for SNCM effective and reasonable application is essential.