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例1,女,30岁.因咳嗽10d就诊,诊断为急性支气管炎.给予林可霉素(上海延安制药厂,批号961007)1.2g加入5%葡萄糖注射液250mL中静滴,30min后突感胸闷、气促声嘶,进而呼吸困难.体检:T37℃,P118次/min,R40次/min,BP15/10kPa;口唇发绀,双肺满布哮鸣音,心律齐.立即停用林可霉素,给予吸氧,静注地塞米松10mg.同时予氨茶碗0.125g,氢化可的松琥珀酸钠0.2g加入5%葡萄糖注射液500ml静滴维持.1h后症状好转,双肺哮鸣音消失.2d后作皮肤斑贴试验阳性,所输液体经细菌、真菌培养,鲎试验均阴性.患者有青霉素过敏史.
Case 1, female, 30 years old, diagnosed as acute bronchitis due to coughing for 10 days, given lincomycin (Shanghai Yan’an Pharmaceutical Factory, batch number 961007) 1.2g added 5% glucose injection 250mL intravenous infusion, 30min after the sudden sense Chest tightness, shortness of breath and hoarseness, and then dyspnea.Physiological examination: T37 ℃, P118 times / min, R40 times / min, BP15 / 10kPa; lips cyanosis, lungs covered with wheeze, Su, give oxygen, intravenous injection of dexamethasone 10mg.At the same time to ammonia tea bowl 0.125g, hydrocortisone sodium succinate 0.2g 5% glucose injection 500ml intravenous infusion to maintain .1h after the symptoms improved, lung wheeze Disappeared .2d after the skin patch test positive, the infusion of fluid by bacteria, fungal culture, 鲎 test were negative .People have penicillin allergy history.