A novel therapeutic target for peripheral nerve injury-related diseases： aminoacyl-tRNA synthetases

• 作 者: Byung Sun Park Seung Geun Yeo
• 机 构: DepartmentofAnatomyandNeurobiology,DepartmentofOtolaryngolgy,DepartmentofAnatomyandCellBiology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2015年10期
• 关键词: 氨基酰-TRNA合成酶 外周神经损伤 药物治疗 相关疾病 脊髓背角神经元 细胞周期调控 周围神经损伤 神经胶质细胞 nerve regeneration ami
• 基金项目: supported by Basic Science Research Program through the National Research Foundation of Korea（NRF）, funded by the Ministry of Science,ICT and Future Planning（2015R1A2A2A01002735 to JJ,2015R1C1A1A02036

Aminoacyl-t RNA synthetases(Amino ARSs) are essential enzymes that perform the first step of protein synthesis. Beyond their original roles, Amino ARSs possess non-canonical functions, such as cell cycle regulation and signal transduction. Therefore, Amin