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目的 探讨青年肺癌 (2 5岁以下 )患者的临床特点、病理分型、误诊原因及影响预后的因素。方法 对我院 1 980— 2 0 0 3年收住的 2 5岁以下青年肺癌 2 8例进行临床回顾性分析。结果 本组病例肺癌均经病理证实。临床症状以刺激性咳嗽 (2 5例 )和痰中带血(1 9例 )为主。病理分型以小细胞未分化癌 (1 1例 )和磷癌 (9例 )为主。误诊率为 46 .4%。TNM分期以Ⅱ期 1 1例 (39.2 % )和Ⅲ期 1 5例 (53 .6 % )为主。 90 .5 %的患者 2年内死亡。结论 2 5岁下青年肺癌就诊时间晚 ,误诊率高 ,病程短 ,预后极差 ,应引起重视 ,凡有呼吸道症状的患者应及时行X线检查 ,细胞学检查 ,纤维支气管镜活检 ,胸膜活检 ,胸腔镜、纵膈镜乃至开胸探查 ,明确诊断和治疗
Objective To investigate the clinical features, pathological types, causes of misdiagnosis and prognostic factors in young patients with lung cancer (below 25 years old). Methods We retrospectively analyzed 28 cases of young lung cancer under 25 years of age housed in our hospital from 1980 to 2003. Results of this group of patients with lung cancer confirmed by pathology. Clinical symptoms were irritating cough (25 cases) and bloody sputum (19 cases). Pathological type of small cell undifferentiated carcinoma (11 cases) and phosphorus cancer (9 cases) based. The misdiagnosis rate was 46.4%. TNM staging was mainly based on 11 cases (39.2%) of stage Ⅱ and 15 cases (53.6%) of stage Ⅲ. Ninety-five percent of patients die within two years. Conclusions 25 years of age under the age of young lung cancer treatment of late, high misdiagnosis rate, short course of disease, poor prognosis, should pay attention to, who have respiratory symptoms should prompt X-ray examination, cytology, fibrobronchial biopsy, pleural biopsy , Thoracoscopy, mediastinoscopy and thoracotomy exploration, a clear diagnosis and treatment