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目的探究对不稳定型心绞(UAP)痛患者应用阿司匹林联合氯吡格雷治疗的效果。方法选取2014年1月-2015年1月收治的UAP患者78例,随机分为常规组与联合组各39例。对常规组患者单纯应用阿司匹林治疗,对联合组患者应用阿司匹林及氯吡格雷治疗。比较2组治疗总有效率及心绞痛发作状况。结果联合组总有效率为92.31%明显优于常规组的74.36%,差异有统计学意义(P<0.05),2组患者治疗前的心绞痛发作频率及发作持续时间相比较差异无统计学意义(P>0.05)。治疗后联合组心绞痛发作频率及发作持续时间均少于(上接20页)常规组,2组比较差异有统计学意义(P<0.05)。结论应用阿司匹林联合氯吡格雷治疗UAP效果良好,可有效控制、降低心绞痛发病率,改善预后。值得临床推广应用。
Objective To investigate the effect of aspirin combined with clopidogrel in patients with unstable angina pectoris (UAP). Methods 78 patients with UAP who were admitted to our hospital from January 2014 to January 2015 were randomly divided into routine and combined groups of 39 patients. Aspirin alone was administered to patients in the conventional group and aspirin and clopidogrel were used in the combination group. The total effective rate of treatment and angina pectoris were compared between the two groups. Results The total effective rate in the combined group was 92.31%, which was significantly higher than that in the conventional group (74.36%), the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the frequency of angina pectoris and the duration of attack before treatment P> 0.05). After treatment, the frequency of episodes of angina pectoris and duration of episodes in the combined group were less than those in the conventional group (up to 20 pages). The difference between the two groups was statistically significant (P <0.05). Conclusion Aspirin and clopidogrel are effective in treating UAP, which can effectively control and reduce the incidence of angina and improve the prognosis. Worthy of clinical application.