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目的 :比较前列地尔 (脂微球制剂 )和丁咯地尔治疗急性脑梗死的疗效。方法 :98例急性脑梗死病人分为两组 ,其中前列地尔组 5 8例 ,男 3 0例 ,女 2 8例 ,年龄 ( 62± 9)岁 ( 4 6～ 80岁 ) ,应用前列地尔 10 μg ,iv ,qd ;疗程 15d ;丁咯地尔组 40例 ,男性 2 4例 ,女性 16例 ,年龄 ( 61± 9)岁 ( 4 4～ 82岁 ) ,应用丁咯地尔 2 5 0mg ,ivgtt ,qd ,疗程 15d。结果 :前列地尔组总有效率 93 % ,高于丁咯地尔组80 % ( P <0 .0 5 )。结论 :前列地尔治疗急性脑梗死疗效显著 ,优于丁咯地尔。
OBJECTIVE: To compare the efficacy of alprostadil (lipid microsphere preparation) and buflomedil in the treatment of acute cerebral infarction. Methods: A total of 98 patients with acute cerebral infarction were divided into two groups. Among them, 58 patients in the alprostadil group, 30 males and 28 females, aged 62 ± 9 years (46 to 80 years) 10 (iv) and iv (qd) for 15 days. Forty patients in the buflomedil group, including 24 males and 16 females, were aged 61 ± 9 years (range 4 to 82 years). Buflomedil 25 0mg, ivgtt, qd, treatment 15d. Results: The total effective rate in the alprostadil group was 93%, which was higher than that in the buflomedil group (80%, P <0.05). Conclusion: Alprostadil is superior to buflomedil in the treatment of acute cerebral infarction.