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本文对24例高血压病伴有脑梗塞和20例高血压伴有短暂脑供血障碍的患者,为预防缺血性中风,在服用降压药方法方面进行初探.试验组于清晨一次服用尼群地平(0.02g),并与传统服药方法(早、中、晚各服0.01g)比较.结果表明:此方法可针对血压的昼夜24小时周期节律性变化,有效避免和控制夜间睡眠时血压降低和清晨觉醒后回升及波动,以达到降低缺血性中风清晨发生率的目的.新服药方法依据“时辰药物学”原理,对从机理上防止缺血性中风昼夜中发病高峰的形成,具有重要意义,并优于传统服药方法,值得临床应用.
In this paper, 24 cases of hypertensive patients with cerebral infarction and 20 cases of hypertension associated with transient cerebral blood supply disorders in patients with ischemic stroke prevention and treatment of antihypertensive drugs were used to explore the test group in the morning taking nitrendipine (0.02g), and compared with the traditional method of taking medicine (morning, middle and late each serving 0.01g) .The results showed that this method could regulate the circadian rhythm of blood pressure 24 hours a day and 24 hours a day and effectively avoid and control the decrease of blood pressure during nighttime sleep And wake up early morning after the rise and fluctuations in order to achieve the purpose of reducing the incidence of ischemic stroke in the new method based on the “time pharmacology” principle, from the mechanism to prevent the pathogenesis of ischemic stroke peak incidence of day and night, is important Meaning, and superior to the traditional method of taking medicine, it is worth clinical application.