Hematotesticular barrier is altered from early stages of liver cirrhosis： Effect of insulin-like gro

• 作 者: InmaCastilla-Cortazar NievesDi
• 机 构: DepartmentofHumanPhysiology,DepartmentofHumanPhysiology,DepartmentofInternalMedicine,DepartmentofInt
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年17期
• 关键词: 血睾 肝硬化 胰岛素 生长因子1 消化系统 AnimalsAtrophyCarbon TetrachlorideEstrogensFollicle Stimul
• 基金项目: Supported by the Spanish Program I+D,SAF 99/0072 and SAF2001/1672

AIM: The pathogenesis of hypogonadism in liver cirrhosis is not well understood. Previous results from our laboratory showed that IGF-1 deficiency might play a pathogenetic role in hypogonadism of cirrhosis. The administration of IGF-1 for a short period