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目的探讨P型Roux-en-Y全胃切除空肠代胃术(PR)对胃癌患者全胃切除术后生活质量的影响。方法实施PR全胃切除术的62例胃癌患者作为实验组,功能性空肠间置代胃重建术(FJI)患者60例作为对照组,所有患者在手术后3周行辅助化疗,观察患者术后生活质量,记录术后并发症发生率。结果实验组手术并发症发生率为11.3%,对照组为13.3%,经卡方检验,差异无统计学意义,P>0.05;实验组术后生活质量评分为(88.2±9.5)分,对照组为(76.6±9.0)分,经t检验,差异有统计学意义,P<0.05。结论 PR消化道重建术对患者生活质量影响较小,并发症发生率低,该术式安全可行。
Objective To investigate the effect of P-type Roux-en-Y total gastrectomy on the quality of life of patients with gastric cancer after total gastrectomy. Methods Sixty-two patients with gastric cancer undergoing total gastrectomy were enrolled in this study. Sixty patients with functional jejunal interpositional gastroesophagectomy (FJI) served as control group. All patients received adjuvant chemotherapy three weeks after operation. Quality of life, record the incidence of postoperative complications. Results The incidence of complications was 11.3% in the experimental group and 13.3% in the control group. There was no significant difference between the two groups (P> 0.05). The postoperative quality of life of the experimental group was (88.2 ± 9.5) (76.6 ± 9.0) points, by t test, the difference was statistically significant, P <0.05. Conclusion PR gastrointestinal reconstruction has a small impact on the quality of life of patients, the incidence of complications is low, the procedure safe and feasible.