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目的：探讨尿微量白蛋白／肌酐（UACR）与2型糖尿病（T2DM）患者视网膜病变（DR）之间的相关性。方法回顾性分析医院收治的256例T2DM患者的临床资料，重点分析其UACR检查结果与眼底摄片资料，并根据UACR水平将256例患者分为尿蛋白正常组155例（UACR水平＜30mg／g）、微量尿蛋白组101例（UACR水平30～300 mg／g），比较2组患者视网膜病变发生率，总结二者之间的相关性。结果微量尿蛋白组患者平均年龄（56.1±2.1）岁、平均病程（12.5±2.9）年、BMI指数（25.5±1.9）kg／m2、收缩压（149.5±8.5）mmHg、2h FPG（15.8±2.1） mmol／L等指标明显高于尿蛋白正常组，差异有统计学意义（P＜0.01）。微量尿蛋白组UACR水平（215.2±12.9）mg／g，DR发生率55.45％，均明显高于尿蛋白正常组，差异有统计学意义（ P＜0.05）。结论 UACR水平高的T2DM患者的视网膜病变发生率偏高，对于高龄、病程长、血压高类T2 DM患者要加强监测尿白蛋白及肌酐，及早发现微血管病变，及早预防视网膜病变的发生。“,”Objective To investigate correlation analysis of urine micro albumin /urine creatinine ratio and type 2 diabetic retinopathy.Methods Clinical data of 256 cases of T2DM patients in our hospital were reviewed , focuses on the a-nalysis of the UACR examination and fundus photo piece of information , and on the basis of UACR levels will 256 cases of pa-tients were randomly divided for proteinuria normal group of 155 cases (UACR levels in 30g/mg below) and urinary micro pro-tein group 101 cases ( UACR level referrals to 30~300 mg/g) , compared two groups of patients with retinopathy incidence and concluded the correlation.Results Microalbuminuria group with mean age (56.1 ±2.1) years old, the average duration of illness (12.5 ±2.9) years, BMI (25.5 ±1.9)kg /m2, systolic blood pressure levels (149.5 ±8.5) mmHg, 2hFPG (15.8 ±2.1) mmol /L and other index was significantly higher than that in normal group (P<0.01); trace group UACR levels (215.2 +12.9 ) there was significantly higher than that in normal group , and the incidence of Dr 55.45%were signif-icantly higher than those in normal group ( P<0.01 ).Conclusion UACR levels in patients with type 2 diabetes retinopathy occurence rate is high, for old age, long course of disease, blood pressure high T2DM patients to strengthen monitoring of uri-nary albumin and creatinine , early detection of microvascular disease , early prevention of the occurrence of retinopathy .