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目的:通过对两种方法保守治疗异位妊娠的结果分析,探讨保守治疗异位妊娠的临床效果。方法:将该院收治的87例异位妊娠患者采用保守治疗,随机分为实验组和对照组,实验组44例,给予米非司酮口服+甲氨蝶呤(MTX)肌注;对照组43例,给予甲氨蝶呤肌注。分别观察两组生命体征的变化,治疗效果及其不良反应。结果:实验组治愈率90.91%,无效率9.09%;对照组治愈率74.42%,无效率25.58%,两组比较有统计学差异(P<0.05);实验组血β人绒毛膜促性腺激素(β-HCG)值在用药后(10.2±2.4)天开始恢复正常,对照组在用药后(14.3±3.0)天开始恢复正常,两组比较有统计学差异(P<0.05);实验组不良反应与对照组比较无统计学差异(P>0.05)。结论:米非司酮联合甲氨蝶呤用药保守治疗异位妊娠安全有效。
OBJECTIVE: To analyze the clinical results of conservative treatment of ectopic pregnancy by analyzing the results of two methods of conservative treatment of ectopic pregnancy. Methods: Eighty-seven patients with ectopic pregnancy admitted to our hospital were treated with conservative treatment and randomly divided into experimental group and control group. In the experimental group, 44 patients were given mifepristone oral + methotrexate (MTX) intramuscular injection. In the control group 43 cases, given methotrexate intramuscular injection. The changes of vital signs, treatment effects and adverse reactions in the two groups were observed respectively. Results: The cure rate of the experimental group was 90.91%, the inefficiency rate was 9.09%. The cure rate of the control group was 74.42%, the inefficiency rate was 25.58%, there was significant difference between the two groups (P <0.05). The serum β-human chorionic gonadotropin β-HCG) returned to normal after (10.2 ± 2.4) days of treatment, while the control group returned to normal after 14.3 ± 3.0 days, with statistical difference (P <0.05); adverse reactions Compared with the control group, there was no significant difference (P> 0.05). Conclusion: Mifepristone combined with methotrexate conservative treatment of ectopic pregnancy safe and effective.