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目的通过对比肺血栓栓塞症(PTE)治疗前后临床表现及CT肺动脉血管造影(CTPA)检查表现的变化,探讨溶栓和抗凝治疗的疗效,以及在PTE治疗过程中复查CTPA的临床价值。方法收集36例确诊PTE患者的完整临床资料及CTPA影像资料,进行回顾性分析。结果本组患者治愈24例(66.67%),好转9例(25.00%),总有效率为91.67%,死亡3例(8.33%)。溶栓或抗凝治疗1周、2周、1个月、3个月栓子个数进行性减少,两两之间差异均具有统计学意义(P均<0.01);溶栓或抗凝治疗6个月后栓子个数进一步减少,但与治疗3个月相比差异无统计学意义(P均>0.05)。结论早期诊断并积极溶栓、抗凝治疗疗效好,CTPA是PTE诊断和疗效评价的有效影像学检查方法,对PTE的治疗具有指导作用。
Objective To compare the clinical manifestation and CT pulmonary angiography (CTPA) before and after the treatment of pulmonary thromboembolism (PTE), explore the curative effect of thrombolysis and anticoagulant therapy, and review the clinical value of CTPA in the treatment of PTE. Methods The complete clinical data and CTPA images of 36 patients with confirmed PTE were collected and analyzed retrospectively. Results The patients were cured in 24 cases (66.67%), improved in 9 cases (25.00%), the total effective rate was 91.67%, 3 patients died (8.33%). Thrombolysis or anticoagulant therapy for 1 week, 2 weeks, 1 month, 3 months, the number of emboli decreased, the difference was statistically significant (P <0.01); thrombolysis or anticoagulant therapy After 6 months, the number of emboli decreased further, but there was no significant difference between the two groups (P> 0.05). Conclusion Early diagnosis and active thrombolysis, anticoagulant therapy is effective, CTPA is an effective imaging diagnosis of PTE and evaluation of imaging methods, the treatment of PTE has a guiding role.