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[目的]观察茵陈四逆散联合熊去氧胆酸胶囊治疗肝内胆管结石疗效。[方法]使用随机平行对照方法,将48例住院患者按抽签法简单随机分为两组。对照组24例熊去氧胆酸胶囊,10mg/kg,1次/d,口服。治疗组24例茵陈四逆散(柴胡、猪苓、泽泻、白术各9g,白芍12g,枳实、甘草各6g,茯苓15g,茵陈50g,白茅根30g),1剂/d,水煎300m L,早晚口服;或磨粉开水送服,3g/次,2次/d;熊去氧胆酸治疗同对照组。连续治疗14d为1疗程。观测临床症状、胆绞痛、肝区痛、肝脾肿大、梗阻性黄疸、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效10例,有效13例,无效1例,总有效率95.83%。对照组显效7例,有效9例,无效8例,总有效率66.67%。治疗组疗效优于对照组(P<0.05)。[结论]茵陈四逆散联合熊去氧胆酸胶囊治疗肝内胆管结石效果显著,值得推广。
[Objective] To observe the effect of Yinchen Sini Powder combined with ursodeoxycholic acid capsule in the treatment of intrahepatic bile duct stones. [Methods] Using randomized parallel control method, 48 inpatients were randomly divided into two groups according to the random selection method. Control group, 24 cases of ursodeoxycholic acid capsules, 10mg / kg, 1 / d, orally. The treatment group, 24 cases of Yin Chen Sini Powder (Bupleurum, Polyporus, Alisma, Atractylodes each 9g, white peony root 12g, citrus aurantium, licorice each 6g, Poria 15g, capillaris 50g, Rhizoma Imperatae) , Decoction 300m L, sooner or later oral; or grinding water delivery service, 3g / time, 2 times / d; ursodeoxycholic acid treatment with the control group. Continuous treatment 14d for a course of treatment. Observation of clinical symptoms, biliary colic, liver pain, hepatosplenomegaly, obstructive jaundice, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] In the treatment group, 10 cases were markedly effective, 13 cases were effective, 1 case was ineffective, and the total effective rate was 95.83%. The control group markedly effective in 7 cases, effective in 9 cases, 8 cases, the total effective rate 66.67%. The treatment group was better than the control group (P <0.05). [Conclusion] Yinchen Sini Decoction combined with ursodeoxycholic acid capsule in the treatment of intrahepatic bile duct stones is significant and worth promoting.