Ran binding protein 9（RanBPM） binds IFN-λR1 in the IFN-λsignaling pathway

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：China_BILLGATES

【摘要】

：

Like the type I interferons(IFNs),the recently discovered cytokine IFN-λ displays antiviral,antiproliferative,and proapoptotic activities,mediated by a heterod

【作者】

：

Junwen Zhang XiaojieCong Jiaji

【机构】

：

NationalLaboratoryofMedicalMolecularBiology,BrainTumorResearchCenter,BeijingLaboratoryofBiomedicalMa

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2017年9期

【关键词】

：

信号通路结合蛋白 RAN IFN-γ γ干扰素相互作用异源二聚体免疫共沉淀 IFN-λ IFN-λR1 interaction RanBPM

【基金项目】

：

supported by the National Natural Science Foundation of China（81302186,81372354,81672478）, the Beijing Natural Science Foundation（7151002）, the Beijing Laboratory of Biomedical Materials Foundation,th

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Like the type I interferons(IFNs),the recently discovered cytokine IFN-λ displays antiviral,antiproliferative,and proapoptotic activities,mediated by a heterodimeric IFN-λ receptor complex composed of a unique IFN-λR1 chain and the IL-10R2 chain.However,t

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Ran binding protein 9（RanBPM） binds IFN-λR1 in the IFN-λsignaling pathway

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