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前列腺素E_1(PGE_1)自1991年起我们首次应用于临床治疗消化性溃疡,取得满意效果,现总结如下。 1 临床资料 1.1 病例选择 本组共观察36例,男26例,女10例,十二指肠球部溃疡(DU)24例,胃溃疡(GU)12例,年龄都在18岁以上。全部病例经胃镜证实为活动性消化性溃疡。其中胃溃疡位于胃角5例,胃窦部5例,幽门2例。 1.2 给药方法 所有患者停用一切治疗溃疡的药物,每日给静点前列腺素E_1 100μg加入5％葡萄糖250ml中,Du疗程为4周。Gu疗程为6周,除记录症状变化外,于第4周末及第6周末作胃镜复查,有的部分患者在2周末作胃镜复查。
Prostaglandin E_1 (PGE_1) Since 1991, we first applied to the clinical treatment of peptic ulcer, and achieved satisfactory results, are summarized as follows. 1 Clinical data 1.1 Case Selection A total of 36 cases were observed in this group, 26 males and 10 females, 24 cases of duodenal ulcer (DU), gastric ulcer (GU) in 12 cases, all over 18 years of age. All cases confirmed by gastroscopy as active peptic ulcer. Gastric ulcer stomach located in 5 cases, 5 cases of gastric antrum, 2 cases of pylorus. 1.2 Methods of administration All patients discontinued treatment of ulcer drugs daily intravenous injection of prostaglandin E_1 100μg 5% glucose 250ml, Du treatment for 4 weeks. Gu treatment for 6 weeks, in addition to record changes in symptoms, at the end of the 4th and 6th weekend for endoscopy, and some patients in 2 weeks for endoscopy.