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很多资料证明大剂量使用维生素会出现危害。作者报道,过量应用维生素B_(6)能引起严重的神经毒性。7名患者自己每天口服2g以上维生素B_6,出现严重的感觉神经疾病,其中有4人严重伤残,但停药后都能恢复。其中有一典型病例:女,27岁,两年前开始口服维生素B_6治疗月经前浮肿,剂量为500mg/日,一年后又增加剂量达5g/日,患者逐渐行动不稳,四肢感觉障碍。停药后两个月症状改善,7个月后走路才不用手杖。
A lot of data prove that high doses of vitamins will be harmful. The authors report that overdosing vitamin B_ (6) can cause severe neurotoxicity. Seven patients daily oral administration of more than 2g of vitamin B_6, a serious sensory nerve disease, of which 4 were severely disabled, but can recover after withdrawal. There is a typical case: female, 27 years old, two years ago began oral vitamin B_6 treatment of premenstrual edema, a dose of 500mg / day, a year later to increase the dose of 5g / day, the patient gradually unsteady movement, limb sensory dysfunction. Two months after discontinuation of symptoms improved, walking after 7 months without a cane.