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目的:临床药师参与泛耐药鲍曼不动杆菌(PRAB)感染患者抗感染治疗,分析了其用药的合理性及其疗效。方法:临床药师参与3例泛耐药鲍曼不动杆菌感染重症患者,并协助临床制订了个体化用药方案。结果:经替加环素与头孢哌酮-舒巴坦等药物抗感染治疗后,患者胸部CT检查示感染灶吸收,体温、血白细胞、C-反应蛋白、氧合指数、血清白蛋白水平及APACHE Ⅱ评分值均有明显好转。结论:临床药师参与治疗泛耐药鲍曼不动杆菌感染患者临床用药的会诊,体现了临床药师以患者为中心的药学服务理念,提高了救治的有效率。
OBJECTIVE: The clinical pharmacists participated in the anti-infective treatment of pan-drug-resistant Acinetobacter baumannii (PRAB) infected patients and analyzed their rationality and efficacy. Methods: Clinical pharmacists participated in 3 cases of pan-drug-resistant Acinetobacter baumannii infection in critically ill patients and assisted in the development of a personalized clinical program. Results: After anti-infective treatment with tigecycline and cefoperazone-sulbactam, the chest CT showed the absorption of the affected area, body temperature, white blood cells, C-reactive protein, oxygenation index, serum albumin and APACHE Ⅱ scores were significantly improved. Conclusion: The participation of clinical pharmacists in clinical treatment of patients with pan-drug-resistant Acinetobacter baumannii infection reflects clinical pharmacists’ patient-centered concept of pharmacy service and improves the efficiency of treatment.