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目的探讨急性ST段抬高型心肌梗死患者血β2微球蛋白等指标与Grace评分的关系。方法入选45例急性ST段抬高型心肌梗死患者,对其进行Grace评分,检测血β2微球蛋白、C-反应蛋白、尿酸、胱抑素C、脂蛋白α值。结果利用多元线性回归分析,剔除了C-反应蛋白、尿酸、胱抑素C、脂蛋白α,建立的方程为:Grace评分=98.486+8.829(β2微球蛋白),Grace评分与β2微球蛋白呈正相关。结论急性ST段抬高型心肌梗死患者血β2微球蛋白越高,其Grace评分亦越高,联合应用Grace评分及β2微球蛋白检测,在对疾病进行早期危险分层、评估预后方面有重要的临床价值。
Objective To investigate the relationship between β2-microglobulin and Grace scores in patients with acute ST-segment elevation myocardial infarction. Methods Forty-five patients with acute ST-elevation myocardial infarction were enrolled. Grace score was applied to detect serum β2-microglobulin, C-reactive protein, uric acid, cystatin C and lipoprotein. Results Using multivariate linear regression analysis, C-reactive protein, uric acid, cystatin C and lipoprotein α were excluded. The established equations were: Grace score = 98.486 + 8.829 (β2 microglobulin), Grace score and β2 microglobulin Was positively correlated. Conclusions The higher the serum β2-microglobulin in patients with acute ST-elevation myocardial infarction, the higher the Grace score. The combination of Grace score and β2-microglobulin test is important in early risk stratification and prognosis evaluation The clinical value.