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低氧是一种重要的生理和病理现象,有研究表明低氧可影响成体干细胞的增殖和分化。牙髓组织在受到外伤或刺激时易处于缺血、低氧状态,低氧对成体干细胞影响的研究进展可以为牙髓干细胞的生物学研究提供思路,本文将从低氧对成体干细胞增殖和分化的影响及其相关调控机制、低氧对牙髓细胞增殖和分化的影响等方面作一综述。
Hypoxia is an important physiological and pathological phenomenon, studies have shown that hypoxia can affect the proliferation and differentiation of adult stem cells. Pulp tissue in trauma or irritation prone to ischemia, hypoxia, the impact of hypoxia on adult stem cells progress can provide ideas for the biological study of dental pulp stem cells, hypoxia on adult stem cell proliferation and differentiation And its related regulatory mechanisms, hypoxia on the proliferation and differentiation of dental pulp and other aspects are reviewed.