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1965年,Lippes报道带Lippes IUD的23例受孕妇女中有4例异位妊娠(17.4%),估计同年美国总人口中的异位妊娠发生率约为0.4%,引起人们的关注。在美国,研究人员对异位妊娠的发生率作了调查,一致发现70年代异位妊娠的发生率增加了。自1965年以来,许多报告提供了IUD使用者异位妊娠危险性的资料,且讨论了使用IUD是否导致异位妊娠的发生率增加。尽管就这个问题已作了大量工作,但仍存在一些未回答的问题。本文对这些问题进行了评价。一、异位妊娠的发生率:IUD使用者与未用者的对比虽然已有许多资料对IUD使用者异位妊娠危险性作了评价,但关于IUD使用者与未用者或用其它避孕方法的妇女比较异位妊娠的相对危险性的资料报导较少。妇女保健研究(WHS)、英国牛津家
In 1965, Lippes reported 4 cases of ectopic pregnancy (17.4%) in 23 pregnant women with Lippes IUD. It is estimated that the incidence of ectopic pregnancy in the U.S. population is about 0.4% in the same year, a cause for concern. In the United States, researchers surveyed the incidence of ectopic pregnancy and found that the incidence of ectopic pregnancy increased in the 1970s. Since 1965, many reports have provided information on the risks of ectopic pregnancy in IUD users and discussed whether the use of IUD leads to an increased incidence of ectopic pregnancies. Although much work has been done on this issue, there are still some unanswered questions. This article evaluates these issues. First, the incidence of ectopic pregnancy: Comparison of IUD users and nonusers Although there are many data to evaluate the risk of ectopic pregnancy of IUD users, but IUD users and non-users or with other methods of contraception Of women compared the relative risk of ectopic pregnancy data reported less. Women’s Health Research (WHS), Oxford, UK