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目的 研究外科手术治疗顽固性癫痫的疗效。方法 2 10例顽固性癫痫患者 ,14 5例经过开颅手术 ,主要行脑皮层电图监测下癫痫病灶切除术 ;45例经过立体定向手术 ,术中微电极定位 ,行选择性杏仁核、海马毁损术 ;2 0例采用X刀治疗。结果 术后随访 13 2例 ,平均随访 1 5a ,疗效满意 78例 ,显著改善 3 0例 ,良好 15例 ,效差 5例 ,无改善 4例 ,显效率为 81 8% ,有效率为 93 2 %。结论 药物难以控制或服药有毒副作用的顽固性癫痫患者 ,只要条件具备 ,应积极行外科治疗 ,其疗效大部分是显著的。
Objective To study the effect of surgery on intractable epilepsy. METHODS: Twenty-five patients with refractory epilepsy were enrolled in this study. One hundred and fifty-five patients with intractable epilepsy underwent craniotomy undergoing epileptic cesarean section undergoing cortical electrogram monitoring. Forty-five patients underwent stereotactic surgery, intraoperative microelectrode localization, selective amygdala, hippocampus Damage surgery; 20 patients treated with X knife. Results 132 cases were followed up for an average of 1 5 years. The curative effect was satisfactory in 78 cases, significantly improved in 30 cases, good in 15 cases and ineffective in 5 cases, with no improvement in 4 cases. The effective rate was 81.8% and the effective rate was 93 2 %. Conclusion Patients with intractable epilepsy who are hard to control or take poisonous side effects should be treated surgically as long as the conditions are met. The curative effect is mostly significant.