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支气管哮喘发病机制复杂,现认为是由多种原因引起的以嗜酸性粒细胞、肥大细胞反应为主的气道慢性炎症性病变。治疗上以抗炎为主,辅以支气管平滑肌松弛药。在此将目前用于治疗该病的药物作一综述。 1 过敏介质阻释剂 1.1 色苷酸钠 对迟发和速发、尤其是外源性哮喘均有良好的预防作用。对儿童过敏性哮喘效果较成人好。患慢性难治性哮喘的儿童应用后大都能部分或完全缓解,为预防儿童哮喘的首选药物。毒性极低,但起效慢,用药数天才开始见效。
The pathogenesis of bronchial asthma is complex, is now considered to be caused by a variety of reasons to eosinophils, mast cell response-based chronic airway inflammation. Anti-inflammatory treatment based, supplemented by bronchial muscle relaxants. The current drugs used to treat the disease are reviewed here. 1 allergic mediator 1.1 sodium acetate for delayed and immediate onset, especially exogenous asthma have a good preventive effect. Allergic asthma in children than adults better. Most children with chronic refractory asthma can be partly or completely relieved after their application, which is the first choice for preventing childhood asthma. Very low toxicity, but slow onset, medication began to bear fruit for several days.