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肿瘤发生是一个多步骤多阶段的过程。外源性致癌物诱导机体某些易感细胞的遗传物质，使之发生变化，进而获得一种具有选择生长优势和克隆扩增的异常增殖细胞即肿瘤细胞。其关键因素在于细胞染色体上原癌基因激活（和）肿瘤抑制基因的失活。本文就近年来与肺癌发生、发展相关的
Tumor development is a multi-step, multi-stage process. Exogenous carcinogens induce the genetic material of certain susceptible cells in the body to change them, thereby obtaining an abnormally proliferating cell that is a tumor cell with selective growth and clonal expansion. The key factor is the activation of proto-oncogene (and) tumor suppressor genes on the chromosomes of cells. This article relates to the occurrence and development of lung cancer in recent years