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微流动通道是微流控芯片的重要组成部分,其加工技术的每一步进化或简化一直为国际学术界与工业界所重视.提出了一种基于微丝的PDMS微流动通道制作技术.该技术利用一些简单的模具辅助固定和布置微丝,然后将PDMS预聚物浇注于模具中浸没微丝并固化,固化后抽出微丝形成PDMS微通道或通道阵列,在与通道垂直的方向上打孔并封装,形成与通道外部物质交换的接口.实际制作通道时可采用商用化的金属微丝(如不锈钢微丝),直径从100～20μm不等.较为详细地介绍了利用这种技术来构建多种拓扑结构的二维或三维通道或通道阵列,例如直通道、交叉通道、弯曲通道等的能力.进一步,基于金属微丝的电磁特性,这样的微通道制作工艺还被应用来构建出适于电磁控制和温度控制的微流动通道装置.最后,通过圆截面微通道的光路分析、微通道内粒子流动的图像测速(Micro-PIV)与微液滴形成实验及分析进一步印证了这种微流动通道制作技术的可行性和适用性。
Microfluidic channel is an important part of microfluidic chip, and every step of its processing technology has been evolved or simplified.As a result, microfilament-based PDMS microfluidic channel fabrication technology has been proposed. A few simple molds are used to fix and arrange the microfilaments. The PDMS prepolymer is poured into the mold to immerse the microfilaments and solidify. After curing, the microfilaments are drawn out to form a PDMS microchannel or array of channels, and holes are perforated in a direction perpendicular to the channels And form an interface for exchanging materials with the outside of the channel. Commercially available metal microfilaments (such as stainless steel microfilaments) can be used to make the channel, and the diameters range from 100 to 20 μm. A detailed description of using this technique to construct The ability of two or three dimensional channels or channel arrays of various topologies, such as straight channels, cross channels, curved channels, etc. Further, based on the electromagnetic properties of the metal microfilaments, such microchannel fabrication processes have also been applied to construct suitable Finally, through the optical path analysis of the circular cross-section microchannel, the particle-flow image velocimetry (Micro-PIV) in the microchannel, Experiments and analysis of formation of micro-droplets further confirm the feasibility and applicability of this micro-flow channel fabrication technology.