论文部分内容阅读
目的观察子宫肌瘤切除术后预防性使用抗生素的临床效果。方法选择2012年1—8月进行子宫肌瘤切除的患者187例,随机分为实验组95例与对照组92例,实验组预防性使用抗生素1 d,使用方法为抗生素溶于100 ml生理盐水,于术后立即快速静脉滴注,术后2 h再应用1次。对照组在实验组基础上,再使用同一抗生素溶于100 ml生理盐水静脉滴注,连续治疗5 d。观察两组患者手术时间、切口感染情况、术后出血量、体温恢复时间和住院时间。计量资料采用t检验,P<0.05为差异有统计学意义。结果两组术后均无切口、感染,实验组住院时间[(5.1±1.0)d]明显短于对照组[(5.7±1.3)d],比较差异有统计学意义(P<0.05)。结论子宫肌瘤切除术后立即快速静脉滴注抗生素可达到预防感染的效果,无特殊情况一般不必追加用药次数。
Objective To observe the clinical effect of prophylactic antibiotics after myomectomy. Methods A total of 187 patients with myomectomy from January to August in 2012 were randomly divided into experimental group (95 cases) and control group (n = 92). The experimental group received prophylactic antibiotics for 1 day. The antibiotics were dissolved in 100 ml of normal saline , Rapid intravenous drip immediately after surgery, 2 h after surgery and then applied 1 time. Control group on the basis of experimental group, then use the same antibiotic dissolved in 100 ml saline intravenous infusion, continuous treatment for 5 d. The operation time, incision infection, postoperative blood loss, body temperature recovery time and hospital stay were observed. Measurement data using t test, P <0.05 for the difference was statistically significant. Results No incision or infection was found in both groups. The hospitalization time in the experimental group (5.1 ± 1.0) d was significantly shorter than that in the control group (5.7 ± 1.3) d (P <0.05). Conclusion Immediate intravenous infusion of antibiotics immediately after resection of myomectomy can achieve the effect of preventing infection, and there is no need to increase the frequency of medication in special circumstances.