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对黄曲霉毒索的研究,近十多年来已有不少报导,大量的调查材料和动物实验证明,黄曲霉毒素B_1(下称AFTB_1),与肝癌病因有密切的关系。但一些调查资料表明,在同一生产队其主粮基本相同,而肝癌往往有家族聚集现象。这种现象是否与肝癌高发家庭贮存粮食不好,粮食被AFTB_1污染较严重,因而摄入AFTB_1量较大致使肝癌高发?为此我们在肝癌高发区——扶绥县,按肝癌发病水平不同社队,在同一生产队选择肝癌户与非肝癌户的成员作为调查对象。采集他们的主粮样品进行AFTB_1测定。同时随访登记各户成员食用主粮的多少,从而推算各个成员对AFTB_1的摄入量。现将调查情况结如下。
The study on the toxicity of aflatoxin has been reported for more than a decade. A large number of investigation materials and animal experiments have proved that aflatoxin B1 (hereinafter referred to as AFTB_1) is closely related to the cause of liver cancer. However, some survey data indicate that the staple food is basically the same in the same production team, and liver cancer often has family clustering. Whether this phenomenon is associated with poor food storage in high-incidence households with liver cancer, food contamination by AFTB_1 is relatively serious, and the high intake of AFTB_1 results in high incidence of liver cancer. For this reason, we report the incidence of liver cancer in Fusui County, a high-risk area for liver cancer. The team selected the members of the liver cancer household and non-liver cancer households as the survey objects in the same production team. Samples of their staple foods were collected for AFTB_1 determination. At the same time follow-up registration of various members of the household food consumption, so as to calculate the individual members of the intake of AFTB_1. The investigation is now summarized as follows.