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近年来许多作者报道冠心病很可能与血小板聚集有关。我们在家兔实验性心肌梗塞模型上曾观察到蒲黄大剂量静脉注射有明显缩小梗塞范围的作用。为了探讨蒲黄抗急性心肌梗塞(AMI)的作用,我们采用Wu,Hoak 氏检测兔体内循环血小板聚集比率 PAR(Platelet Aggregation Ratio),观察了蒲黄对血小板聚集的影响,现报告如下。材料与方法一、试液与实验方法,采用高素荣及罗正耀报道的方法(北京医学院学报1982;14(1):
In recent years many authors have reported that coronary heart disease is probably related to platelet aggregation. In our model of experimental myocardial infarction in rabbits, large doses of intravenous injection of Puhuang have been observed to significantly reduce infarct size. To investigate the effect of Puhuang against acute myocardial infarction (AMI), we used Wu, Hoak’s method to detect platelet aggregation ratio (PAR) in rabbits and observed the effect of Puhuang on platelet aggregation. The report is as follows. Materials and Methods 1. Test solution and experimental method, using methods reported by Gao Surong and Luo Zhengyao (Journal of Beijing Medical College 1982;14(1):