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本文简述了磺胺甲(口恶)唑缩合工艺由原来水相反应改为氯仿相反应,改进后总收率由40%左右提高到45%的生产水平。
This article describes the sulfonamides (oxazole) condensation process from the original water phase reaction to chloroform phase reaction, the improved total yield from about 40% to 45% of the production level.