糖皮质激素对抗生素治疗未足月胎膜早破疗效的影响

• 作 者: 王文
• 出 处: 国外医学.妇产科学分册
• 发表日期: 1999年01期
• 关键词: 未足月胎膜早破 PPROM 糖皮质激素 母儿预后 随机对照试验 绒毛膜羊膜炎 对母 诊断标准 周和 脑室内出血

本文对比单独用抗生素与同时用精皮质激素治疗未足月胎膜早破(PPROM)对母婴的影响。1986～1993年间发表的关于应用糖皮质激素和抗生素治疗PPROM的5项研究共509例,其中254例应刚抗生素及糖皮质激素,255例只用抗生素,并比较了7项研究共657例用与不用抗生素治疗PPROM对母儿预后影响。入选的研究均为随机对照试验,并在病例数、抗生素治疗方案、孕周和诊断标准具有可比

This article compares the effects of antibiotic alone with corticosteroids on maternal and neonatal unprofitable premature rupture of membranes (PPROM). Five studies published in 1986-1993 on the use of glucocorticoids and antibiotics in the treatment of PPROM were performed in 509 patients, of whom 254 were antibiotics and glucocorticoids, 255 were antibiotics only and were compared with 657 in 7 studies Effect of PPROM without antibiotics on the prognosis of maternal and child. Selected studies were randomized controlled trials and were comparable in number of cases, antibiotic regimens, gestational weeks, and diagnostic criteria