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研究表明人参可提高老年鼠心肌、肺等外周组织β受体含量,但对老年大鼠脑组织β受体的影响却较少报导.本研究目的观察人参对老年大鼠各脑区β受体含量的影响.实验选用SD老年大白鼠24只,分高浓度人参组(lg/500g体重/d)、低浓度人参组(0.25g/500g/d)、老年对照组.应用人参(吉林生晒参)水煎液灌服老年鼠,3周后用放射配基受体结合分析法测定大鼠大脑皮质、小海马、脑β受体含量,结果如下:大脑皮质、海马、小脑β受体 含量高浓度人参组分别为47.37±4.21、43.26±3.21和24.19±3.31;低浓度人参组分别为39.77± 3.68、39.26± 3.27和20.19±3.81;老年对照组分别为40.65±3.73、35.64±3.37和19.25±3.31.高浓度人参组的大脑皮质、海马β受体含量与老年对照组和低浓度人参组比较,P<0.05.本实验结果显示灌服高浓度人参大鼠大脑皮质、海马β受体含量有明显增高,而小脑组织β
Studies have shown that ginseng can increase β-receptor levels in peripheral tissues such as myocardium and lungs in aged rats, but the effects of β-receptors on brain tissue in older rats are rarely reported. The purpose of this study was to observe the effects of ginseng on β-receptors in brain regions of aged rats. The effect of the content. 24 SD SD rats were used in the experiment. The rats were divided into high-dose ginseng group (lg/500g body weight/d), low-dose ginseng group (0.25g/500g/d), and elderly control group. The application of ginseng (Jilin Sunshade) Ginsenosides were decocted into aged mice. After 3 weeks, the cerebral cortex, small hippocampus, and brain β-receptor levels were measured using radioligand receptor binding assays. The results were as follows: Cerebral cortex, hippocampus, and cerebellar β-receptor levels The high-dose ginseng group was 47.37±4.21, 43.26±3.21, and 24.19±3.31 respectively; the low-dose ginseng group was 39.77±3.68, 39.26±3.27, and 20.19±3.81, respectively; the old control group was 40.65±3.73, 35.64±3.37, and 19.25 respectively. ±3.31. High-concentration ginseng group cerebral cortex, hippocampus β receptor content compared with the old control group and low concentration of ginseng group, P <0.05. The experimental results show that high-concentration ginseng rat cerebral cortex, hippocampus β receptor content Obviously increased, while cerebellar tissue β